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Why you're stiff in the morning: Your body suppresses inflammation when you sleep at night

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New research published online in The FASEB Journal, describes a protein created by the body's "biological clock" that actively represses inflammatory pathways within the affected limbs during the night. This protein, called CRYPTOCHROME, has proven anti-inflammatory effects in cultured cells and presents new opportunities for the development of drugs that may be used to treat inflammatory diseases and conditions, such as arthritis.

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