Rush-hour for neutrophils
Researchers at Ludwig-Maximilians-Universitaet (LMU) in Munich have shown that circadian oscillations in the influx of immune cells into the damaged tissue play a crucial role in exacerbating the...
View ArticleCannabinoids remove plaque-forming Alzheimer's proteins from brain cells
Salk Institute scientists have found preliminary evidence that tetrahydrocannabinol (THC) and other compounds found in marijuana can promote the cellular removal of amyloid beta, a toxic protein...
View ArticleScientists identify an essential role of the immune receptor CD69 in psoriasis
Scientists at the Centro de Investigaciones Cardiovasculares Carlos III (CNIC) have defined the key role of an immune-system receptor in the development of psoriasis, suggesting that it could serve as...
View ArticleResearch brings new understanding of chronic inflammatory disease
Research from life scientists at The University of Manchester has shone new light on the way cells tune in to different inflammatory signals to understand what is happening in the body.
View ArticleEffect of cholesterol medicine on inflammatory diseases mapped
The cholesterol medicine simvastatin, which is one of the most commonly used pharmaceuticals in the world, also has a beneficial effect on the immune defence system with regard to diseases such as type...
View ArticleWeight loss from bariatric surgery appears to reverse premature aging
Weight loss from bariatric surgery appears to reverse the premature aging associated with obesity, according to research presented today at Frontiers in CardioVascular Biology (FCVB) 2016.1 Patients...
View ArticleThe colon is defended from bacteria by a self-sacrificing sentinel cell
A lone Sentinel cell monitors and coordinates the defense of the entrance to the colon's most sensitive parts. The Sentinel cell detects nearby bacteria and signals to a line of defensive cells to send...
View ArticleReactive oxygen species—fueling or putting the brakes on inflammation?
Reactive oxygen species (ROS) such as peroxides and superoxides are important signalling molecules in an organism's regulation of metabolism and inflammation. Accumulation of ROS have been linked to...
View ArticleLong noncoding RNA found to quell inflammation
A long non-coding RNA (lincRNA) - called lincRNA-EPS - responsible for regulating innate immunity has been identified by a team of scientists at the University of Massachusetts Medical School....
View ArticleHybrid immune cells in early-stage lung cancer spur anti-tumor T cells to action
The microenvironment of tumors is a mix of cell types, mostly comprised of inflammatory cells. White blood cells, recruited from the blood and bone marrow, represent a significant portion of these...
View ArticleDNA-modulating drug attenuates lung inflammation in mice
Patients with cystic fibrosis (CF) suffer from chronic respiratory infections, primarily caused by Pseudomonas aeruginosa, which lead to airway inflammation and damage. Several recent studies have...
View ArticleResearchers reveal how an inflammatory response to ceramic scaffolds promotes...
In their mission to design new biomaterials that promote tissue regeneration, Drexel University researchers have identified how inflammation, when precisely controlled, is crucial to bone repair.
View ArticleNo platelets, no immune response
When a virus attacks our organism, an inflammation appears on the affected area which triggers off the process of immune defence within our body. White blood cells (such as neutrophils and inflammatory...
View ArticlePromoting regulatory T cell production may help control atherosclerosis
In atherosclerosis, the buildup of cholesterol deposits in arteries poses a major risk for cardiovascular diseases like heart attack and stroke. As cholesterol accumulates, it triggers an inflammatory...
View ArticleWhy you're stiff in the morning: Your body suppresses inflammation when you...
New research published online in The FASEB Journal, describes a protein created by the body's "biological clock" that actively represses inflammatory pathways within the affected limbs during the...
View ArticleHow to engineer a stronger immune system
With a trick of engineering, scientists at the Gladstone Institutes improved a potential weapon against inflammation and autoimmune disorders. Their work could one day benefit patients who suffer from...
View ArticleNew class of molecules play key role in influencing the immune system
In a study published online this week in Science Translational Medicine, investigators from Brigham and Women's Hospital and the Santa Lucia Foundation in Rome report that resolvins and maresins,...
View ArticleEnigmatic molecules maintain equilibrium between fighting infection,...
Special RNA molecules called long non-coding RNAs (lncRNAs) are key controllers for maintaining immune health when fighting infection or preventing inflammatory disorders, according to research led by...
View ArticleScientists uncover the way a common cell enzyme alerts the body to invading...
Biomedical investigators at Cedars-Sinai have identified an enzyme found in all human cells that alerts the body to invading bacteria and jump-starts the immune system.
View ArticleOne more reason to swear off tobacco: The inflammatory trap induced by nicotine
An Umeå-based team in collaboration with US researchers reveals a new link between nicotine and inflammation. They report that nicotine strongly activates immune cells to release DNA fibres decorated...
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