Special RNA molecules called long non-coding RNAs (lncRNAs) are key controllers for maintaining immune health when fighting infection or preventing inflammatory disorders, according to research led by Jorge Henao-Mejia, MD, PhD, an assistant professor of Pathology and Laboratory Medicine in the Perelman School of Medicine at the University of Pennsylvania. The discovery offers a potential drug target for several inflammatory disorders characterized by an abnormal lifespan in a group of white blood cells, which can lead to organ damage.
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