Curb your immune enthusiasm
Normally when we think of viruses, from the common cold to HIV, we want to boost people's immunity to fight them. But for scientists who develop therapeutic viruses (to, for example, target cancer...
View ArticleTracking movement of immune cells identifies key first steps in inflammatory...
Using a novel approach for imaging the movement of immune cells in living animals, researchers from the Massachusetts General Hospital (MGH) Center for Immunology and Inflammatory Diseases (CIID) have...
View ArticleResearchers help the body protect itself against inflammation and colon cancer
Could inflammatory bowel disease and colon cancer be prevented by changing the shape of a single protein?
View ArticleFirst stem cell study in the world for cystic fibrosis opens
A 39-year-old man with cystic fibrosis (CF) made history by becoming the first person in the world to receive human adult stem cells in a new research study that researchers hope will someday lead to...
View ArticleCruciferous vegetables help the immune system to fight intestinal pathogens
A study in mice shows that eating cruciferous vegetables—including broccoli, kale and cauliflower - helps the immune system to fight intestinal pathogens. The research might have implications for...
View ArticleA pathway controlling inflammatory responses aids recovery after heart attack
After a heart attack, or myocardial infarction, a patient's long-term prognosis depends on the ability of the heart tissue to heal and remodel. Immune system activation and inflammatory responses that...
View ArticleScientists discover how epithelial cells maintain constant cell numbers
Research published today in Nature from scientists at Huntsman Cancer Institute (HCI) at the University of Utah shows how epithelial cells naturally turn over, maintaining constant numbers between cell...
View ArticleNew compounds increase glucose uptake into fat cells
New molecules which scientists hope could one day become drugs for both cancer and diabetes have been created at the University of Bath.
View ArticleCytotoxic immune cell in sick and healthy skin a key to understanding vitiligo
With the aid of thousands of skin biopsies and over a hundred kilograms of skin, researchers at Karolinska Institutet have observed how two subgroups of immune cell behave in healthy skin. This...
View ArticleInflammatory disease trigger revealed
Institute scientists have revealed a potent inflammatory molecule released by dying cells triggers inflammation during necroptosis, a recently described form of cell death linked to inflammatory disease.
View ArticleGenetic variant linked to overactive inflammatory response
Researchers at Cardiff University have discovered that genetic variation is the reason why some immune systems overreact to viruses.
View ArticleCell death in gut implicated in bowel disease
The natural life cycle of cells that line the intestine is critical to preserving stable conditions in the gut, according to new research led by a Weill Cornell Medicine investigator. The findings may...
View ArticleNew PET radiotracer identifies inflammation in life-threatening atherosclerosis
In the featured article of the March 2017 issue of The Journal of Nuclear Medicine, researchers demonstrate that a new positron emission tomography (PET) radiotracer, gallium-68 (Ga-68)-pentixafor, can...
View ArticleEpigenetic enzyme found to be lacking in some patients with Crohn's disease
A Massachusetts General Hospital (MGH) research team has found how a variant in an important epigenetic enzyme—previously associated by population-based genetic studies with Crohn's disease and other...
View ArticleStudy highlights possible Achilles' heel in key immune memory cells
The capacity for memory isn't exclusive to the brain. The immune system, with its sprawling network of diverse cell types, can recall the pathogens it meets, helping it to swiftly neutralize those...
View ArticleProtein proves influential to healthy immune system
Researchers have discovered that the protein Myb plays a vital role in keeping our immune system healthy, and preventing the development of immune and inflammatory diseases.
View ArticleStudy shows how BPA may affect inflammatory breast cancer
The chemical bisphenol A, or BPA, appears to aid the survival of inflammatory breast cancer cells, revealing a potential mechanism for how the disease grows, according to a study led by researchers in...
View ArticleNew report links early life antibiotic use to inflammatory gut diseases in...
A new research report in the Journal of Leukocyte Biology involving mice shows that antibiotic use very early in life that alters the normal development/growth of gut bacteria, may contribute to the...
View ArticleScientists develop new antibody for bowel disease
UConn molecular and cell biologist Michael Lynes and an international team of researchers have been awarded a patent for a novel antibody therapeutic that may prove to be safer in the treatment of...
View ArticleCytokine controls immune cells that trigger inflammatory bowel disease, study...
A certain cytokine, or small protein that helps cells communicate during immune responses, can control whether immune cells promote or suppress inflammatory bowel disease, a finding that could lead to...
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