Researchers reveal role of gene in IBD
Inside a healthy gut, bacteria and immune cells maintain a delicate balance. If that balance is disturbed, a condition called inflammatory bowel disease or IBD can result. Patients with IBD can...
View ArticleSmoking decreases MAIT cells, implicated in the pathology of autoimmune diseases
New research published in the May 2017 issue of the Journal of Leukocyte Biology provides another reason why smoking tobacco is harmful. In the report, researchers from Denmark show that smokers have...
View ArticleStudy pinpoints key pathway in inflammation and aging
In patients with colitis, a serious condition affecting the gut, the immune system turns against the body's own microbes, causing inflammation. To combat this inflammation, scientists have focused in...
View ArticleResearchers uncover key role for microRNA in inflammatory bowel disease
An international team of researchers has discovered that a microRNA produced by certain white blood cells can prevent excessive inflammation in the intestine. The study, "Myeloid-derived miR-223...
View ArticleScientists pinpoint key bowel disease gene
A key gene that helps to explain an underlying cause of incurable bowel disorders such as Crohn's disease has been identified by scientists.
View ArticleGenetic malfunction causes hyperactive inflammation and cancer susceptibility
Mutations in an immune gene underlie two inflammatory skin diseases, according to research led by A*STAR scientists. These findings reveal a mechanism that could control inflammation and offer routes...
View ArticleActemra approved for certain blood vessel inflammation
(HealthDay)—The injected drug Actemra (tocilizumab) has been approved by the U.S. Food and Drug Administration to treat adults with giant cell arteritis, an inflammation of the blood vessels (vasculitis).
View ArticleResearchers suppress fibrosis chemical signal to block haywire healing
An injured body always seeks to heal. But that process is far from simple. A host of cells organize to restore what was damaged. Then, critically, the process tapers off. And when it doesn't, the...
View ArticleResearchers find piece in inflammatory disease puzzle
Inflammation is the process by which the body responds to injury or infection but when this process becomes out of control it can cause disease. Monash Biomedicine Discovery Institute (BDI)...
View ArticleResearchers identify surface proteins responsible for navigating immune cells...
The protein tags that adorn immune cells and engage with receptors to promote inflammation in the body's endothelial tissues are not what they were thought to be. An investigation by Saudi Arabia's...
View ArticleNot such a 'simple' sugar—glucose may help fight cancer and inflammatory disease
Glucose - commonly referred to as a 'simple' sugar - may actually be crucial in the fight against cancer and inflammatory disease as scientists have just discovered a new role in which it stimulates...
View ArticleFat tissue may impede radiotherapy for breast cancer patients
According to research published online in The FASEB Journal, repeated irradiation of breast fat (also known as adipose tissue) produces an inflammatory response that ultimately reduces the efficiency...
View ArticleGut check: A molecule that balances the immune system in the gut
A healthy gut requires a molecule called gp96 to train the immune system to tolerate food and normal microbes, report researchers at the Medical University of South Carolina (MUSC) in the May 19, 2017...
View ArticleCellular stress increases the probability of developing autoimmune diseases
A team of researchers led by Marc Veldhoen at the Instituto de Medicina Molecular (iMM), Lisboa, has found that cellular stress enhances the activation of immune cells implicated in many chronic...
View ArticleCharacterization of innate lymphoid cells with an advanced cytometric...
A family of cells key to the immune system's frontline defenses has been described in greater detail than ever before. A*STAR researchers hope their analysis will help those seeking to target them to...
View ArticleBacterial superantigens turn our immune cells to the dark side
A subpopulation of immune cells that normally fend off pathogens can turn against the host during certain infections, a new study publishing on June 20 in the open access journal PLOS Biology reveals.
View ArticleLutein may suppress inflammation
Lutein, a nutrient found in several highly coloured vegetables and fruits, can suppress inflammation, according to a new study by researchers at Linköping University, Sweden. The results, published in...
View ArticleHow a few drops of blood led to a breakthrough in immunology
Scientists from the Research Institute of the McGill University Health Centre (RI-MUHC) may have cracked the code to understanding the function of special cells called regulatory T Cells. Treg cells,...
View ArticleTargeting 'broken' metabolism in immune cells reduces inflammatory disease
The team, led by researchers at Imperial College London, Queen Mary University of London and Ergon Pharmaceuticals, believes the approach could offer new hope in the treatment of inflammatory...
View ArticleNew target could soothe the itch of inflammatory skin conditions
Existing medicines could offer a new way to treat inflammatory skin conditions, researchers at the Walter and Eliza Hall Institute and the Royal Melbourne Hospital have revealed.
View Article